rPeptide products are for research purposes only. Not for human consumption.
Biotin Tau-352
Tau is a family of major neuronal microtubule associated proteins that are found in the neurofibrillary tangles (NFT) in Alzheimer’s disease. Tau promotes the assembly and maintains the structure of microtubules in neuronal cells1,2,3. An avi-tag was added to the C-terminus of the tau-352 sequence for in vivo biotinylation of the protein. Biotinylation was verified by ELISA and western blot. Biotinylated tau-352 can serve as a probe in many research applications including immunohistochemistry, localization studies4, and affinity assays5, without the need for further labeling or a specific antibody.
Categories: Proteins, Tau, Tau Fragments, Tau Labeled
Specifications
Amino Acid Sequence
Description & Background
Tau is a family of major neuronal microtubule associated proteins that are found in the neurofibrillary tangles (NFT) in Alzheimer’s disease. Tau promotes the assembly and maintains the structure of microtubules in neuronal cells1,2,3. An avi-tag was added to the C-terminus of the tau-352 sequence for in vivo biotinylation of the protein. Biotinylation was verified by ELISA and western blot. Biotinylated tau-352 can serve as a probe in many research applications including immunohistochemistry, localization studies4, and affinity assays5, without the need for further labeling or a specific antibody.