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Benztropine Mesylate
Centrally acting M1 muscarinic acetylcholine receptor antagonist (Ki=0.59 nM, rat) 1. Also inhibits the dopamine transporter (Ki=160 nM) 2. Enhances remyelination and significantly decreases clinical severity in the experimental autoimmune encephalomyelitis model of relapsing-remitting multiple sclerosis alone or in combination with immunosuppressive agents 3. Inhibits hepatitis C virus infection 4.
Categories: Neurodegenerative Related Compounds
Specifications
Amino Acid Sequence
Description & Background
Centrally acting M1 muscarinic acetylcholine receptor antagonist (Ki=0.59 nM, rat) 1. Also inhibits the dopamine transporter (Ki=160 nM) 2. Enhances remyelination and significantly decreases clinical severity in the experimental autoimmune encephalomyelitis model of relapsing-remitting multiple sclerosis alone or in combination with immunosuppressive agents 3. Inhibits hepatitis C virus infection 4.