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HomeProductsNeurodegenerative Related CompoundsBexarotene

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rPeptide
N-3032-1
High-Purity Recombinant
Batch Tested • Purity Guaranteed • Fast US & Worldwide Dispatch
SKU: N-3032-1

Bexarotene

$133.00

A highly potent and selective retinoid X receptor (RXR) agonist (EC50=28, 25, 20 nM for RXRalpha, beta, gamma respectively) 1. Clinically useful antineoplastic agent for cutaneous T-cell lymphoma 2. Causes complete regression of mammary carcinoma 3. Bexarotene significantly increases clearance of soluble B-amyloid in a mouse Alzheimer′s model and increases cognitive ability 4. Reverses apoE4-driven brain pathology and behavioral deficitsin vivo 5.

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Categories: Neurodegenerative Related Compounds

Specifications

Physical State: White lyophilized powder
Temperature Storage: -20°C
Temperature Shipping: Ambient
Source: Recombinant. Expressed in E. coli
Purity: >97% by Mass Spec.
Molecular Mass: Theoretical

Amino Acid Sequence

D A E F R H D S G Y E V H H Q K L V F F A E D V G S N K G A I I G L M V G G V V

Description & Background

A highly potent and selective retinoid X receptor (RXR) agonist (EC50=28, 25, 20 nM for RXRalpha, beta, gamma respectively) 1. Clinically useful antineoplastic agent for cutaneous T-cell lymphoma 2. Causes complete regression of mammary carcinoma 3. Bexarotene significantly increases clearance of soluble B-amyloid in a mouse Alzheimer′s model and increases cognitive ability 4. Reverses apoE4-driven brain pathology and behavioral deficitsin vivo 5.

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