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rPeptide
N-3024-1
High-Purity Recombinant
Batch Tested • Purity Guaranteed • Fast US & Worldwide Dispatch
SKU: N-3024-1

FK-506

$190.00

FK-506 induces immunosuppression by inhibiting T cell proliferation. Inhibits FKBP12 and calcineurin (IC50ca. 1 nM) 1. Reduces neuroinflammation and neuro-degeneration in an alpha-synuclein-based rat model of Parkinson’s disease 2. Increases the rate of axonal regeneration following crush injury in a rat model 3. Cell permeable.

1
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Categories: Neurodegenerative Related Compounds

Specifications

Physical State: White lyophilized powder
Temperature Storage: -20°C
Temperature Shipping: Ambient
Source: Recombinant. Expressed in E. coli
Purity: >97% by Mass Spec.
Molecular Mass: Theoretical

Amino Acid Sequence

D A E F R H D S G Y E V H H Q K L V F F A E D V G S N K G A I I G L M V G G V V

Description & Background

FK-506 induces immunosuppression by inhibiting T cell proliferation. Inhibits FKBP12 and calcineurin (IC50ca. 1 nM) 1. Reduces neuroinflammation and neuro-degeneration in an alpha-synuclein-based rat model of Parkinson’s disease 2. Increases the rate of axonal regeneration following crush injury in a rat model 3. Cell permeable.

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